Originally built as the college gymnasium in 1920, Players Theatre later became a classroom and theatre facility.

At one point KWAR-FM headquarters were located in Players Theatre, and college chapel services were held there. During the 1990-91 academic year, it served as temporary headquarters for the art department after the Art Building was razed to make room for the Fine Arts Center.

During construction of the Vogel Library, Players Theatre housed the library's reference collection and service areas. It was used as a science teaching space during the construction of the Science Center in 2002-03 and 2003-04.